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HLA Marker Comparison
Compare selected HLA markers between members who choose to add compatible DNA data.
Gene Pool Science
The Science Behind Gene Pool
Gene Pool adds optional HLA marker context to donor and co-parent profiles, then uses mutual preferences to support stable matching. The people involved make every decision.
Genetic Compatibility Matching
Gene Pool can compare selected HLA markers between donors and recipients who choose to add compatible DNA data. The comparison adds another layer of context to the profiles members review.
HLA similarity and difference sit alongside location, preferences, and family-building goals. Members remain in control of whom they contact and what information they share.
HLA Compatibility
The Human Leukocyte Antigen (HLA) system plays a central role in immune recognition and has been studied in reproduction and mate choice. Gene Pool presents HLA similarity and difference as one comparison signal alongside the information members choose to share.
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Shared Profile Context
Place HLA similarity and difference alongside location, preferences, and family-building goals.
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Research You Can Inspect
Follow the published research that informs how Gene Pool presents HLA context.
Research-Based Approach
The Gene Pool evidence library brings together research across genetics, immunology, reproductive biology, and mate-choice science. These studies provide context, not an individual forecast of fertility, pregnancy, or child health.
Jokiniemi et al., 2025
Jokiniemi et al., 2020
Meuleman et al., 2015
Mora-Sanchez et al., 2019
Ober, 1999
Ober et al., 1998
Ober et al., 1993
Havlicek et al., 2020
Stable Matching Algorithm
Stable allocation and mutual preference
Gene Pool uses stable-matching concepts associated with the Gale-Shapley algorithm . The 2012 Nobel Memorial Prize in Economic Sciences recognized Lloyd Shapley and Alvin Roth for the theory of stable allocations and the practice of market design.
For donor and co-parent discovery, stable matching helps organize mutual preferences so participants can review relevant profiles and decide whom to contact. Optional HLA context can be one input. Stable describes the allocation rule, not a medical or reproductive outcome.
Stable allocation frameworkMutual preferences
Start Your Family Journey
Bring profile preferences and optional HLA context together as you explore donors or co-parents.